The Philippines has one of the fastest growing number of Human Immunodeficiency Virus (HIV) cases in the world. HIV is a retrovirus that weakens the immune system of a person that may lead to Acquired Immunodeficiency Syndrome (AIDS) if left untreated. Diagnosis of HIV is done using a blood test where the number of CD4 cells are counted. However, detection of this disease is usually late since symptoms such as fever, sore throat, rash, and weight loss show up two to four weeks after the infection (Carinelli et al., 2015).Biosensor is an emerging technology for the next generation of healthcare. Bahadir and Sezgintürk (2015) defines biosesnsor as an analytical device that combines biological entities such as proteins, enzymes, and phages to a compatible transducer to convert biological interactions into detectable electronic signals that can be accurately measured and analyzed. It is composed of two main parts which are the receptor and transducer. The receptor is responsible for reception and transformation of received stimuli into electrical energy. On the other hand, the transducer converts the electrical energy into analytical signals which can be studied in an electronic form (Ali et al., 2017).Different biosensors have been broadly applied in analyte detection for their simplicity, potential ability, and sensitivity. From those studies, the use of electrochemical biosensors is considered as a promising new tool for identification of HIV for its reduced cross-contamination and shorter identification time compared to conventional methods.(Rodrigo et al., 2014) The researcher plans to use electrochemical biosensors as an alternative and accessible device for early diagnosis of HIV which can prevent the acquisition of AIDS. The research aspires to help in providing solution to the fast epidemic of HIV in the Philippines. SCOPE AND DELIMITATIONThe main focus of this research is on the accuracy, efficacy, and effectiveness of the electrochemical biosensor in the detection and analysis of the glycoproteins CD4+. Early detection was the main purpose of the project and thus clinical trials for real patients are not included in the study. SIGNIFICANCE OF THE STUDYThe Philippines has one of the fastest growing number of cases of HIV worldwide for lack of knowledge in using contraceptives to prevent HIV transmission. (World Health Organization, 2017) This study aims to provide Filipinos an alternative and accessible device for early detection and diagnosis of HIV.