The prescribed title question of this essay concern how our knowledge increases when we have doubt in them however with little confidence we tend to act as if we know more knowledge at hand. To try to provide an answer to the statement made in the prescribed title, One has to define what confidence is when one has little knowledge, and what doubt is when it comes to knowledge. To reference this I will try to put the Dunning Kruger effect, where it states that; It’s a phenomenal where people who are really qualified tend to underestimate their ability , whereas people who are underqualified tend to over fluctuate their sense of self- importance. Hence, the purpose of these essay is to discuss the statement with two areas of knowledge. The two areas of Knowledge that will be use in hand with the prescribed title will be Human sciences and Natural sciences, it will allows us to come with evidences that will go in hand with the Prescribed title or go against the statement as a whole. And the two ways of knowing that will be used will be Intuition and reason, due to their in depth form of knowledge and the processes of forming our conclusion without us being aware of our mental processes. To able to discusses the statement above a main knowledge question has to be formed; ” To what extent does knowledge increase doubt”. However, to further discuss the statement a second knowledge was established, “How does intuition and reason increase our doubt on Knowledge”. Additionally a third question was chosen, To what extent is confidence the product of knowledge? ” The first knowledge question to be showcase is “To what extent does knowledge increase doubt,” to be able to approach this knowledge question one has to form a claim, which states that ” Doubt is the main tool that increase knowledge. Doubt is defined as the feelings of uncertainty towards the truth, and a French philosopher known as Rene Descartes, stated that doubt is the origin of wisdom, and in some cases you can doubt everything except one thing and that is the fact about doubt. As one may say , the more doubt you have on something, the more curious you will get, thus try to contradict each step ahead of you. However such doubts on knowledge have been encountered by me so many times, especially in the human science. In Biology I was skeptic the first time I had that cancer can be cured with the help of gene therapy, which will be taken as real life example of the scientific methods. Genes are coded messages that tell cells how to make proteins and in gene therapy, the aim is to re-introduce the body with new gene where they would attack the antigens that attacks the body, and if all things goes well, the patient will be in remediation, however the FDA’s approval on genethrapy was a groundbreaking in United states. This gene therapy is designed to treat an often-lethal type of blood and bone marrow cancer that affects children and young adults. the approach that Novartis suggested is Known as a CAR-T therapy, and the results were shown remarkable in patients recovery.At the beginning , the gene therapy was marked as Kymriah and it soul purpose was to treat patient´s T-cells as a type of immune cell, the procedure was done as , the patient´s T-cells were extracted and cryogenically frozen . Hence the cells were genetically altered to have a new gene that codes for protein, and its called Chimeric antigen receptors, and they are proteins that targets the T-cells and kills leukemia cells with a specific antigen on their surface. The genetically modified cells are then infused back in to the patient., Hence this real life situation was are real good example of doubt is the main tool that increases knowledge. And in time knowledge will increase and more doubt in concept will lead to more research which ultimately lead to increase in knowledge. However a counterclaim to this is doubt is not the only main tool that will increase knowledge. Knowledge adds doubts, which in turn leads to more knowledge. In radio perspective one can reason out without them having doubt. In my opinion knowledge is the main concept when we have doubt for example: Someone who estimates their chances in winning a lottery, they will base their concept to logic and their chances will be fifty:fifty, however with knowledge in association with doubt , their chances will slightly increase.On the other hand in order to define what confidence means in the provide statement , another knowledge question has to be established “How does intuition and reason increase our confidence on Knowledge?” Both reason and Intuition are way of knowing that shapes and retrieve information by drawing conclusions from facts, evidence in our mental processes. Confidence is define as a feeling or consciousness of one’s powers or of reliance on one’s circumstances. The area of knowledge that will be associated with this knowledge question is human science, and for a real-life situation in psychology class. We learnt that human beings are mental representation in the uncertainty of that is wrong or rights in people’s opinion toward knowledge. We learnt what schema theory, which says that we have schema models in our brain that makes sense in everything that we know, hence everytime we learn something new, we tend to fit to our existing schema or come up with an new one. A claim that will approach the knowledge question states as Reason and Intuition both increases confidence in knowledge. since psychology is not regular science and that many researcher argue about to what extent is psychology considered a scientific. Psychology isn’t a real science it is usually accompanied by mentions of some psychologists or researchers engaging in unscientific things and its fair share of pseudoscience., However psychology is all about experiments and to validate how reliable the finding are, and to produce either a positive or negative correlation in a study which will also lead to producing a cause effect relationship in knowledge. Reason and intuition are both encounter to an extent that it will lead to an increase to knowledge in psychology . Nonessential for example how accurate can we preserve knowledge and in psychology we can use deductive reasoning to extreme knowledge to some extent it gives us an objective truth. Hence a counterclaim to this: In certain context reason and intuition can overlaps with our increase in knowledge in extent such as in psychology where human relationship and social culture are obtained through non experimental scientific research like observation where informations are gathered and analysed through any means of scientific methods where both deductive and inductive analysis and theories will be over represented, by doing so one can reason out that there is no no difference between human science or natural science, on the other hand in economics it tries to unify human science and psychology by combining both intuition and reason. Since the study of economic shows that problems may arise from human being and that we are fixated on finding problems that are beyond our limitation on how far our needs are placed. However, it hard to determine how much of the population needs to be taken into consideration in behavioural patterns, as it counts as clear patterns and overlaps weather patterns exists or not and thus will lead to more insight on knowledge.Contemplating a contingency conclusion; a third knowledge question was formed “To what extent is confidence the product of knowledge?” With confidence we tend to brag blissfully about thing we know more, however if we associate our knowledge, on a concept our doubt will definitely increase, so again we will take human sciences and natural sciences into considerations once more, particularly the concept of neurotransmission and their effect on human behavior in psychology and neurobiology and behaviour in biology. Hence the question that will be arise from this will be is the knowledge from human science go hand in hand with natural sciences. So in psychology for example: we know that the nerves are neurons that are building blocks of behaviours.(Martinez and Kesner 1991) had done a research on mices, where the give mices two type of neurotransmitter. One was to block acetylcholine receptors and the other one was to block the role of cholinesterase in. the limitation to this study was to question to what extent has this finding be generated hence more knowledge would be to answer the question yes, there are some extent that human science and natural sciences would collide with one another and that knowledge will be produced depending on the question that is arisen. To conclude in general, the first knowledge question To what extent does knowledge increase doubt it depends to the extent that one is willing to gain knowledge, however, doubt plays a huge role when it comes to determining what is right and what’s is wrong in one’s perspective however the second knowledge question , How does intuition and reason increase our confidence on Knowledge, with more knowledge one starts to be over confidence however, using reasoning and intuition on knowledge, one might based it on our intuition when it comes to knowledge but reasoning out will lead to more searching in knowledge and gain more confidence on it and the final knowledge question, it depends on situations that one can base their knowledge to an extent that it can relate another aspect where doubt can arisen.